Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.500 Therapeutic CTD_human Heme oxygenase-1 inhibits rat and human breast cancer cell proliferation: mutual cross inhibition with indoleamine 2,3-dioxygenase. 16319139

2005

Entrez Id: 5747
Gene Symbol: PTK2
PTK2
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.500 Therapeutic CTD_human Mammary gland-specific ablation of focal adhesion kinase reduces the incidence of p53-mediated mammary tumour formation. 24809783

2014

Entrez Id: 6696
Gene Symbol: SPP1
SPP1
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.300 Therapeutic CTD_human Osteopontin is a potential target gene in mouse mammary cancer chemoprevention by Se-methylselenocysteine. 15318939

2004

Entrez Id: 331
Gene Symbol: XIAP
XIAP
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.300 Therapeutic CTD_human Structural and functional protection of photoreceptors from MNU-induced retinal degeneration by the X-linked inhibitor of apoptosis. 12766084

2003

Entrez Id: 174
Gene Symbol: AFP
AFP
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.300 Therapeutic CTD_human Prevention of N-methyl-N-nitrosourea-induced breast cancer by alpha-fetoprotein (AFP)-derived peptide, a peptide derived from the active site of AFP. 16322315

2005

Entrez Id: 5020
Gene Symbol: OXT
OXT
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.300 Therapeutic CTD_human Oxytocin and oxytocin-analogue F314 inhibit cell proliferation and tumor growth of rat and mouse mammary carcinomas. 8647655

1996

Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.300 Therapeutic CTD_human Lack of ABCG2 shortens latency of BRCA1-deficient mammary tumors and this is not affected by genistein or resveratrol. 22767648

2012

Entrez Id: 5020
Gene Symbol: OXT
OXT
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.300 Therapeutic CTD_human Oxytocin and oxytocin receptors in cancer cells and proliferation. 15089975

2004

Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.300 Therapeutic CTD_human Enhanced anticancer effect of the combination of cisplatin and TRAIL in triple-negative breast tumor cells. 21252285

2011

Entrez Id: 902
Gene Symbol: CCNH
CCNH
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.500 Biomarker CTD_human Allelic imbalance and altered expression of genes in chromosome 2q11-2q16 from rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 12606953

2003

Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.500 Biomarker CTD_human Infrequent mutation of Ha-ras and p53 in rat mammary carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 8185828

1994

Entrez Id: 301
Gene Symbol: ANXA1
ANXA1
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.500 Biomarker CTD_human cDNA microarray profiling of rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthracene. 12376462

2002

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.500 Biomarker CTD_human CDK4/6 inhibition provides a potent adjunct to Her2-targeted therapies in preclinical breast cancer models. 25221644

2014

Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.500 Biomarker CTD_human Lack of ABCG2 shortens latency of BRCA1-deficient mammary tumors and this is not affected by genistein or resveratrol. 22767648

2012

Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.500 Biomarker CTD_human Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas. 16316942

2005

Entrez Id: 6776
Gene Symbol: STAT5A
STAT5A
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.500 Biomarker CTD_human Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas. 16316942

2005

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.500 Biomarker CTD_human The effect of a DNA repair gene on cellular invasiveness: XRCC3 over-expression in breast cancer cells. 21283680

2011

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.500 Biomarker CTD_human Analysis of EGFR, TGF-alpha, neu and c-myc in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced mammary tumors using RT-PCR. 8603490

1995

Entrez Id: 6776
Gene Symbol: STAT5A
STAT5A
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.500 Biomarker CTD_human cDNA microarray profiling of rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthracene. 12376462

2002

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.500 Biomarker CTD_human Steroid hormone receptor expression and proliferation in rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 15637090

2005

Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.500 Biomarker CTD_human High susceptibility of transgenic rats carrying the human c-Ha-ras proto-oncogene to chemically-induced mammary carcinogenesis. 11376698

2001

Entrez Id: 301
Gene Symbol: ANXA1
ANXA1
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.500 Biomarker CTD_human Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas. 16316942

2005

Entrez Id: 1019
Gene Symbol: CDK4
CDK4
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.500 Biomarker CTD_human Deregulation of the cyclin D1/Cdk4 retinoblastoma pathway in rat mammary gland carcinomas induced by the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 14522882

2003

Entrez Id: 1019
Gene Symbol: CDK4
CDK4
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.500 Biomarker CTD_human cDNA microarray profiling of rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthracene. 12376462

2002

Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.500 Biomarker CTD_human Deregulation of the cyclin D1/Cdk4 retinoblastoma pathway in rat mammary gland carcinomas induced by the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 14522882

2003